{"id":36379,"date":"2026-02-04T15:44:00","date_gmt":"2026-02-04T07:44:00","guid":{"rendered":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/"},"modified":"2026-02-04T15:44:00","modified_gmt":"2026-02-04T07:44:00","slug":"scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments","status":"publish","type":"post","link":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/","title":{"rendered":"Scientists identify mutation behind resistance to new schizophrenia treatments"},"content":{"rendered":"<p>Researchers in Australia have discovered a rare genetic mutation that could explain why some people do not respond to newer schizophrenia treatments.<br \/>The study, published in Genomic Psychiatry, reveals that an inherited change in the brain can completely block the function of the trace amine-associated receptor 1 (TAAR1), a receptor targeted by newer schizophrenia drugs making them ineffective, this according to a statement from Australia&#8217;s Flinders University.<br \/>Whilst TAAR1-based therapies have emerged as a leading alternative medication for treating schizophrenia, people with this mutation are unlikely to benefit from them, said the study&#8217;s principal investigator Pramod Nair, senior research fellow at Flinders University.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers in Australia have discovered a rare genetic mutation that could explain why some people do not respond to newer schizophrenia treatments.The study, published in Genomic Psychiatry, reveals that an inherited change in the brain can completely block the function of the trace amine-associated receptor 1 (TAAR1), a receptor targeted by newer schizophrenia drugs making [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-36379","post","type-post","status-publish","format-standard","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Scientists identify mutation behind resistance to new schizophrenia treatments - Metro Plus<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists identify mutation behind resistance to new schizophrenia treatments - Metro Plus\" \/>\n<meta property=\"og:description\" content=\"Researchers in Australia have discovered a rare genetic mutation that could explain why some people do not respond to newer schizophrenia treatments.The study, published in Genomic Psychiatry, reveals that an inherited change in the brain can completely block the function of the trace amine-associated receptor 1 (TAAR1), a receptor targeted by newer schizophrenia drugs making [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/\" \/>\n<meta property=\"og:site_name\" content=\"Metro Plus\" \/>\n<meta property=\"article:published_time\" content=\"2026-02-04T07:44:00+00:00\" \/>\n<meta name=\"author\" content=\"Metro Admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Metro Admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/\"},\"author\":{\"name\":\"Metro Admin\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#\\\/schema\\\/person\\\/6bbe2f487494b6f04d542440127c7895\"},\"headline\":\"Scientists identify mutation behind resistance to new schizophrenia treatments\",\"datePublished\":\"2026-02-04T07:44:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/\"},\"wordCount\":114,\"publisher\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#organization\"},\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/\",\"url\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/\",\"name\":\"Scientists identify mutation behind resistance to new schizophrenia treatments - Metro Plus\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#website\"},\"datePublished\":\"2026-02-04T07:44:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/2026\\\/02\\\/04\\\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Scientists identify mutation behind resistance to new schizophrenia treatments\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#website\",\"url\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/\",\"name\":\"Metro Plus\",\"description\":\"Metro Plus\",\"publisher\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#organization\",\"name\":\"Metro Plus\",\"url\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/cropped-metroplus1044.png\",\"contentUrl\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/cropped-metroplus1044.png\",\"width\":240,\"height\":169,\"caption\":\"Metro Plus\"},\"image\":{\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/#\\\/schema\\\/person\\\/6bbe2f487494b6f04d542440127c7895\",\"name\":\"Metro Admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/406741887e2b499d9f2b2d4de7792c34f5c1bdcb01722828c2466332139b8510?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/406741887e2b499d9f2b2d4de7792c34f5c1bdcb01722828c2466332139b8510?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/406741887e2b499d9f2b2d4de7792c34f5c1bdcb01722828c2466332139b8510?s=96&d=mm&r=g\",\"caption\":\"Metro Admin\"},\"url\":\"https:\\\/\\\/multimetro.hk\\\/plus\\\/author\\\/metroadmin\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Scientists identify mutation behind resistance to new schizophrenia treatments - Metro Plus","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/","og_locale":"en_US","og_type":"article","og_title":"Scientists identify mutation behind resistance to new schizophrenia treatments - Metro Plus","og_description":"Researchers in Australia have discovered a rare genetic mutation that could explain why some people do not respond to newer schizophrenia treatments.The study, published in Genomic Psychiatry, reveals that an inherited change in the brain can completely block the function of the trace amine-associated receptor 1 (TAAR1), a receptor targeted by newer schizophrenia drugs making [&hellip;]","og_url":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/","og_site_name":"Metro Plus","article_published_time":"2026-02-04T07:44:00+00:00","author":"Metro Admin","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Metro Admin","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/#article","isPartOf":{"@id":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/"},"author":{"name":"Metro Admin","@id":"https:\/\/multimetro.hk\/plus\/#\/schema\/person\/6bbe2f487494b6f04d542440127c7895"},"headline":"Scientists identify mutation behind resistance to new schizophrenia treatments","datePublished":"2026-02-04T07:44:00+00:00","mainEntityOfPage":{"@id":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/"},"wordCount":114,"publisher":{"@id":"https:\/\/multimetro.hk\/plus\/#organization"},"articleSection":["News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/","url":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/","name":"Scientists identify mutation behind resistance to new schizophrenia treatments - Metro Plus","isPartOf":{"@id":"https:\/\/multimetro.hk\/plus\/#website"},"datePublished":"2026-02-04T07:44:00+00:00","breadcrumb":{"@id":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/multimetro.hk\/plus\/2026\/02\/04\/scientists-identify-mutation-behind-resistance-to-new-schizophrenia-treatments\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/multimetro.hk\/plus\/"},{"@type":"ListItem","position":2,"name":"Scientists identify mutation behind resistance to new schizophrenia treatments"}]},{"@type":"WebSite","@id":"https:\/\/multimetro.hk\/plus\/#website","url":"https:\/\/multimetro.hk\/plus\/","name":"Metro Plus","description":"Metro Plus","publisher":{"@id":"https:\/\/multimetro.hk\/plus\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/multimetro.hk\/plus\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/multimetro.hk\/plus\/#organization","name":"Metro Plus","url":"https:\/\/multimetro.hk\/plus\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/multimetro.hk\/plus\/#\/schema\/logo\/image\/","url":"https:\/\/multimetro.hk\/plus\/wp-content\/uploads\/2022\/09\/cropped-metroplus1044.png","contentUrl":"https:\/\/multimetro.hk\/plus\/wp-content\/uploads\/2022\/09\/cropped-metroplus1044.png","width":240,"height":169,"caption":"Metro Plus"},"image":{"@id":"https:\/\/multimetro.hk\/plus\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/multimetro.hk\/plus\/#\/schema\/person\/6bbe2f487494b6f04d542440127c7895","name":"Metro Admin","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/406741887e2b499d9f2b2d4de7792c34f5c1bdcb01722828c2466332139b8510?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/406741887e2b499d9f2b2d4de7792c34f5c1bdcb01722828c2466332139b8510?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/406741887e2b499d9f2b2d4de7792c34f5c1bdcb01722828c2466332139b8510?s=96&d=mm&r=g","caption":"Metro Admin"},"url":"https:\/\/multimetro.hk\/plus\/author\/metroadmin\/"}]}},"_links":{"self":[{"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/posts\/36379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/comments?post=36379"}],"version-history":[{"count":0,"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/posts\/36379\/revisions"}],"wp:attachment":[{"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/media?parent=36379"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/categories?post=36379"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/multimetro.hk\/plus\/wp-json\/wp\/v2\/tags?post=36379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}